Closing Gaps in Health and Care

  • Mitochondrial proteins protect heart cells from chemotherapy damage

    Jul 24, 2023 1:45 pm
    Human induced pluripotent stem cell-derived heart cells (cardiomyocytes) show the cardiac proteins actinin (red) and troponin T (green) as well as the nucleus (blue).

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    • Human induced pluripotent stem cell-derived heart cells (cardiomyocytes) show the cardiac proteins actinin (red) and troponin T (green) as well as the nucleus (blue).

    University of Illinois Chicago researchers have found that when heart cells are put under stress from certain types of chemotherapy drugs, some enzymes move from the cell's mitochondria into its nucleus, where they are able to keep the cells alive.